Triggering sporulation inBacillus subtiliswith artificial two-component systems reveals the importance of proper Spo0A activation dynamics
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منابع مشابه
Triggering sporulation in Bacillus subtilis with artificial two-component systems reveals the importance of proper Spo0A activation dynamics.
Sporulation initiation in Bacillus subtilis is controlled by the phosphorylated form of the master regulator Spo0A which controls transcription of a multitude of sporulation genes. In this study, we investigated the importance of temporal dynamics of phosphorylated Spo0A (Spo0A∼P) accumulation by rewiring the network controlling its phosphorylation. We showed that simultaneous induction of KinC...
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15 صفحه اولThe Bacillus subtilis SinR protein is a repressor of the key sporulation gene spo0A.
SinR is a pleiotropic DNA binding protein that is essential for the late-growth processes of competence and motility in Bacillus subtilis and is also a repressor of others, e.g., sporulation and subtilisin synthesis. In this report, we show that SinR, in addition to being an inhibitor of sporulation stage II gene expression, is a repressor of the key early sporulation gene spo0A. The sporulatio...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2013
ISSN: 0950-382X
DOI: 10.1111/mmi.12357